Unlock the dark potential of Diablo 4’s Season of Blood with Vampiric Powers-unique abilities that can transform your gameplay and give you an edge against the undead hordes. From your first encounter in the seasonal questline to mastering the Sanguine Circle, discover how to unlock, upgrade, and activate all Vampiric Powers before the season ends, and harness the full might of blood magic on PC, PlayStation, and Xbox.
Every season in Diablo 4 is a chance to try out different builds for your favorite classes. Vampiric Powers give you even more options. If all you want is to start the grind and use some blood-induced magic, you can jump into it pretty quickly: As you start the season and complete the very first couple of Season Quests, you get “The Hunter’s Chase” quest, which introduces Vampiric Powers and gives you access to your Sanguine Circle.
Our Diablo 4 guide will show you learn how to unlock and equip Vampiric Powers. You can also find a complete list of all Vampiric Powers you have access to in the season to plan your next build.
How to unlock and equip Vampiric Powers in Diablo 4
To unlock and equip Vampiric Powers in Diablo 4’s Season of Blood, you first need to progress through the initial seasonal quests, particularly “The Hunter’s Chase,” where you meet Hunter Erys and unlock the Vampiric Powers tab in your character menu, marked by a blood drop icon with a green leaf. After unlocking this feature, you gain your first Vampiric Power. To unlock additional powers, you must spend Potent Blood, which is earned by defeating Blood Seekers, participating in Blood Harvest events, and completing other vampire-related activities. Once unlocked, Vampiric Powers can be equipped by dragging them into one of five slots in the Sanguine Circle above your character’s equipment. However, these powers only activate if your equipped armor contains the required Pacts-special consumables or inherent armor bonuses in Ferocity, Divinity, or Eternity categories. Managing these Pacts on your gear is essential to activate and benefit from the Vampiric Powers you have equipped.
To unlock most of the Vampiric Powers available during the Season of the Blood, you need to go to the Vampiric Power tab in the Character menu.

Then, you need to spend Potent Blood, a currency introduced in Diablo 4 season 2. You gain Potent Blood by completing contents such as quests, participating in Blood Harvests, and chests. Spending 25 Potent Blood will activate a pop-up window featuring three Vampiric Powers will appear. You can choose to unlock or upgrade one of the three. You can’t choose which powers will appear and you can only upgrade already unlocked powers.
There are, however, seven Vampiric Powers that you can’t unlock using this system. You can get two powers – Sanguine Brace and Accursed Touch – by increasing your Hunter’s Acclaim Tier. You earn the other five – Metamorphosis, Moonrise, Undying, Ravenous, Hectic, and Accursed Touch – by completing the Season Quests.

Equipping Vampiric Powers is directly related to Pacts. To equip a Vampiric Power, you need to select – among those you’ve unlocked – the abilities you want and put them in your Sanguine Circle. However, a Vampiric Power can be either Active or Inactive in the circle. To activate them, you must have the Pacts required by the power’s Activation Cost.
Having an Inactive power in your circle doesn’t affect you negatively, but it’s a waste of potential in case you have a suitable replacement.
Diablo 4 Pacts explained
Pacts in Diablo 4’s Season of Blood are essential gear affixes that enable the activation of Vampiric Powers. There are three types of Pacts-Ferocity, Divinity, and Eternity-each represented by distinct symbols. Vampiric Powers require a specific number and type of these Pacts to be equipped and activated. Players obtain Pacts primarily through Pact Armor, which comes with varying amounts and types of Pacts, and they can customize these Pacts using Pact-granting and Pact-cleansing items. Each armor piece has a maximum number of Pacts it can hold, and managing these Pacts effectively is key to unlocking and using the full range of Vampiric Powers during the Season of Blood.
During the Diablo 4 season 2, helms, chest armors, gloves, pants, and boots come with a new attribute: Pacts. There are three different types: Ferocity, Eternity, and Divinity. A piece of gear can come with more than one of these.

Pacts are used to activate Vampiric Powers, making these new attributes a core mechanic in season 2. Depending on the powers you want to use, you must look for pieces that have the quantity of Pacts you need. While you inevitably earn gear with the Pacts necessary for your build, there are a few methods to depend less on random numbers.
By completing dungeons and opening Seeker’s Caches in Blood Harvest areas, you can find seasonal consumables called the Pact of Ferocity, Pact of Eternity, or Pact of Divinity, which allow you to add one point of a specific Pact to a piece of gear. In case luck is not on your side, you can craft these three items by talking to Alchemists. Each of them costs 250 Potent Blood.

Other important items related to Pacts are the Cleansing Acids. These are used to remove Pacts from a specific piece of gear. There are four types of acids, three that remove two points of a specific Pact and one that removes all of them from a piece. Acids might seem contradictory but they are actually pretty useful when you want to use a new piece of gear and need it to have specific Pacts. Since there is a limit of points of Pacts each piece can have, cleaning them becomes necessary to find the best set of gear.
All Vampiric Powers in Diablo 4, plus Pact costs
In Diablo 4 Season of Blood, players can unlock and equip up to five Vampiric Powers simultaneously, enhancing their abilities with unique effects. To activate these powers, players must equip armor pieces containing the corresponding Pacts-Ferocity, Divinity, and Eternity-which serve as the activation cost for each power. Vampiric Powers are unlocked and upgraded using Potent Blood, a seasonal resource earned through quests and events. Each power requires specific combinations of Pacts, ranging from minor powers needing one or two Pacts to major powers demanding six. This system allows players to customize their builds strategically by selecting powers that match the Pacts on their gear, enabling powerful synergies and playstyles.
There are 22 different Vampiric Powers in Diablo 4. Here’s a complete list of all Vampiric Powers, their abilities, and their associated Pact costs:
- Domination: It increases the damage you deal by 12% to enemies that are Stunned, Immobilized, Frozen, or Feared. They are killed if they aren’t an Elite and are also Injured. (Activation Cost: 1 Pact of Ferocity.)
- Undying: By casting skills, you’re healed for 1.5% of your Life. This value doubles when you’re below 50% of Life. (Activation Cost: 1 Pact of Eternity.)
- Sanguine Brace: Killing an enemy gives you Fortify for 3% of your Base Life. You gain a bonus of 4% of Critical Strike Chance when you have more Fortify than half of your Maximum Life. (Activation Cost: 1 Pact of Eternity and 1 Pact of Divinity.)
- Feed the Coven:Lucky Hit – The attacks of Conjuration, Companion, Minion and Far Familiar have a 30% chance of restoring 10 Primary Resource and increasing your damage by 10% for 4 seconds. (Activation Cost: 1 Pact of Eternity.)
- Infection: Direct damage infects enemies with Pox. After 8 stacks, they take from 52 to 77 [30%] of Poison damage. (Activation Cost: 1 Pact of Ferocity.)
- Anticipation: In addition to reducing the cooldown of your Ultimate Skills by 20%, this ability buffs the damage caused by these skills by 6% based on the number of nearby enemies that are affected by your Damage Over Time effects. (Activation Cost: 1 Pact of Divinity.)
- Resilience: With this ability, you gain 1% of Damage Reduction for each 3% of Life that you miss. (Activation Cost: 2 Pacts of Eternity.)
- Prey on the Weak: It increases the damage you deal to Vulnerable enemies by 8%. Enemies are Vulnerable as they are affected by a Vampiric Curse from any of your other Vampiric Powers. (Activation Cost: 2 Pact of Ferocity.)
- Ravenous: Lucky Hit – You have up to 20% chance to have your Attack Speed increased in 20% of your Total Movement for 6 seconds. Activation Cost: 3 Pact of Ferocity.
- Hectic: One of your active Cooldowns is reduced by 1 second for every 5 Basic Skills you use. (Activation Cost: 3 Pact of Divinity.)
- Hemomancy: With this ability, attacking deals 40% of your Maximum Life as Physical Damage every 4 seconds to nearby enemies and you’re healed in 1% of your Maximum Life for each enemy damaged. (Activation Cost: 3 Pact of Eternity.)
- Coven’s Fangs: Conjuration, Companion, Minion, and Bat Familiar deal 26% more damage to Crowd Controlled enemies and when a Lucky Hit lands there is a 30% chance of them inflicting Vampiric Curse to enemies. (Activation Cost: 2 Pact of Divinity.)
- Terror: You have a 7% chance to cause Fear and Slow by 80% nearby enemies for 2 seconds when hit. Critical Strikes are guaranteed to enemies who are Feared. (Activation Cost: 1 Pact of Ferocity, 1 Pact of Divinity, 1 Pact of Eternity.)
- Rampart: After not moving for 3 seconds, you gain a Barrier for 20% of your Maximum Life for 6 seconds. This effect happens only once every 20 seconds. (Activation Cost: 1 Pact of Divinity, 1 Pact of Eternity.)
- Jagged Spikes: With this ability, Thorns has a 10% chance to cause 150% increased damage and inflict Chill to enemies for 8%. (Activation Cost: 1 Pact of Ferocity, 1 Pact of Divinity.)
- Metamorphosis: Evading turns you into a cloud of bats, becoming Unstoppable for 2 seconds. In addition to this, deals 138 to 206 Physical damage and inflict Vampiric Curse to enemies along your path. (Activation Cost: 2 Pact of Ferocity, 2 Pact of Divinity, 2 Pact of Eternity.)
- Moonrise: Hitting an enemy with a Basic Skill grants 4% of Attack Speed for 10 seconds. This effect can be stacked up to 5 times. When max stacks are reached, you enter a Vampiric Bloodrage state, gaining 80% Basic Skill damage and 15% Movement Speed for 10 seconds. (Activation Cost: 6 Pact of Ferocity.)
- Call Familiar: Upon using a Mastery, Weapon Mastery, Macabre, Wrath, or Imbuement Skill invokes a Bat Familiar that deals 69 to 103 of Physical damage to enemies with a 30% chance to Stun. (Activation Cost: 3 Pact of Ferocity, 3 Pact of Divinity.)
- Bathe in Blood: Creates a pool of blood around you when Channeling a Skill. Your skill deals 20% increased damage and you gain 30% Damage Reduction while channeling the skill. (Activation Cost: 3 Pact of Divinity, 3 Pact of Eternity.)
- Accursed Touch: Lucky Hit – You have up to a 22% chance to inflict Vampiric Curse on enemies. Afflicted enemies have a 15% chance to spread it to other enemies. Besides that, Vampiric Curse’s souls deal 100% increased damage. (Activation Cost: 6 Pact of Divinity.)
- Blood Boil: When your Core Skills Overpower an enemy, 3 Volatile Blood Drops spawn. Collecting a Volatile Blood Drop causes it to explore, causing 103 to 155 Physical damage to nearby enemies. Every 40 seconds, your next skill is guaranteed to Overpower. (Activation Cost: 6 Pact of Eternity.)
- Flowing Veins: Increases the Damage Over Time you deal to enemies that are moving or affected by a Vampiric Curse by 30%. (Activation Cost: 2 Pact of Ferocity, 2 Pact of Divinity, 2 Pact of Eternity.)
What secret strategies can help me unlock all Vampiric Powers fast
Secret Strategies to Unlock All Vampiric Powers Fast in Diablo 4
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Focus on Blood Harvest Events: The most efficient way to farm Potent Blood, the currency needed to unlock and upgrade Vampiric Powers, is by repeatedly completing Blood Harvest events and Grim Harvest activities in the Blood Harvest zones. These events grant large amounts of experience, loot, and crucially, Potent Blood drops.
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Optimize Event Timing and Efficiency: Plan your gameplay sessions around the availability of these Blood Harvest events to maximize your Potent Blood farming. Efficiently cycling through these events while managing your resources will speed up unlocking and upgrading powers significantly.
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Prioritize Unlocking Over Upgrading Initially: Every 25 Potent Blood lets you unlock one new power or upgrade an existing one, but the unlock only requires one point. To maximize the number of powers unlocked quickly, choose new powers first before upgrading.
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Complete Seasonal Quests Early: Progress through the Season of Blood’s seasonal questline, especially quests like The Hunter’s Chase, to gain initial access to Vampiric Powers and some unique powers that can only be unlocked through quests.
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Use the Vampiric Power Tab Efficiently: Access the Vampiric Power tab next to your equipment menu to spend Potent Blood strategically. Since the powers offered are random each time, spend Potent Blood thoughtfully to unlock a broad range of powers before focusing on upgrades.
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Leverage Lucky Hits and Crowd Control: Some Vampiric Powers synergize with crowd control and lucky hit mechanics, making combat more efficient and accelerating blood farming indirectly.
By combining focused farming of Blood Harvest events, strategic spending of Potent Blood, and advancing quickly through seasonal quests, you can unlock and upgrade all Vampiric Powers faster than usual.
What are the most efficient ways to farm blood and legendary drops quickly
Most Efficient Ways to Farm Blood and Legendary Drops Quickly in Diablo 4
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Blood Maiden Ritual in Helltides: This is widely regarded as the fastest and most efficient method to farm legendary gear and blood. During Helltides, focus on the Blood Maiden event, which yields a high volume of legendary drops and Potent Blood. Contribute at least one heart to the ritual pedestal to start the event and use consumables like Mindcage Elixir to boost efficiency. In the last 10 minutes of the event, open as many chests as possible with your embers to maximize loot.
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Helltides Overall: Beyond the Blood Maiden ritual, running Helltides consistently is the best way to gather a large number of legendary items. The density of enemies and event rewards make it ideal for fast farming.
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Head Hunt Seasonal Activity: Running Head Hunt zones is excellent for farming gem fragments, gold, and legendary drops. These zones feature many elite monsters and events that drop valuable crafting materials and gear. Prioritize Grim Favor activities, cocoon events, and loot goblins for the best returns.
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Group Farming: Farming in groups increases monster density and speeds up clear times, which improves the efficiency of farming legendaries and blood.
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Target High-Difficulty Areas: Playing at higher difficulty levels increases the drop rate of rare and legendary items, making it worthwhile to farm in more challenging zones or events.
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Open Chests and Use Resources Efficiently: During timed events like Blood Maiden, save and use embers to open chests, which often contain legendary items and blood currency.
By focusing on Helltides with an emphasis on the Blood Maiden ritual, leveraging seasonal activities like Head Hunt, and farming in groups at higher difficulties, you can rapidly accumulate both Potent Blood and legendary gear in Diablo 4.
